The article titled „Silver Colloid Nanoparticles, Characterization, and Their Antibacterial Activity“ exceeded 1,500 citations in 2020 (according to the WoS database). This significant response reflects the long-term relevance of the silver nanoparticle’s extraordinary antibacterial, antiviral, and antiproliferative properties in medical applications. The work was conducted in collaboration with three research institutes – Palacky University in Olomouc, Institute of Physics of Materials in Brno, and Florida Institute of Technology in Melbourne (USA).
The authors designed and verified effective silver nanoparticle synthesis methods leading to narrow distribution of nanoparticle morphologies in order to control the required nanoparticle properties. They proved nanoparticle antimicrobial effect on gram-positive and gram-negative bacteria, including strains of bacteria resistant to antibiotic treatment (e.g. MRSA). The results confirmed a bactericidal effect and detected the dependence of the bactericidal activity on the nanoparticle size.
Article link: https://pubs.acs.org/doi/10.1021/jp063826h
The transmission electron microscope images show silver nanoparticles obtained by reduction of [Ag (NH3) 2] + with four carbohydrates: glucose (A), galactose (B), lactose (C) and maltose (D). The resulting morphologies differ in the size of the nanoparticles.