Institute of Physics of Materials AS CR, v. v. i. > Projects > Influence of microstructure and surface treatments on hydrogen intake in bio-compatible alloys

Influence of microstructure and surface treatments on hydrogen intake in bio-compatible alloys

Investigatorprof. RNDr. Antonín Dlouhý, CSc.
Number of Project20-11321S
Internal Project Number320310
AgencyGrantová agentura České republiky
Duration2020-01-01 - 2022-12-31

Bio-compatible metallic implants, subjected to an aggressive in-vivo attack, absorb hydrogen which may positively reduce a release rate of toxic ions but causes a loss of ductility. In order to understand this contradiction, the proposed research focuses on interactions between microstructure of NiTi and Ti alloys and interstitial hydrogen. We address two topical opened questions: (i) how controlled variations of grain size, dislocation density and nano-structured surfaces affect hydrogen absorption/desorption and (ii) why the absorbed hydrogen reduces the rate by which toxic Ni and Ti ions are released into the body fluids. Were the project granted, we expect the following results: (i) understanding mechanism which govern distributions of hydrogen atoms over NiTi and Ti lattice sites conditioned by local microstructural states, (ii) discover the optimum hydrogen pre-charging which improves alloy stability without a detrimental ductility effect and (iii) new set of data on biomolecular mechanisms which control reactions of cell cultures to hydrogen pre-charged NiTi and Ti alloys.


Šromová V., Sobola D., Kaspar P.: A brief review of bone cell function and importance. Cells 12 (2023) 2576


Štefančík M., Válková L., Veverková J., Weiser A., Dlouhý A., Ryba L., Pávková Goldbergová M.: NiTi alloys exposure alters miR-124 expression in physiological and osteoarthritic osteoblasts. Acta Chir Orthop Traumatol Cech. 89 (2022) 370-375

Vrchovecká K., Weiser A., Přibyl J., Kuta J., Holzer J., Pávková Goldbergová M., Sobola D., Dlouhý A.: A release of Ti-ions from nanostructured titanium oxide surfaces. Surfaces and Interfaces 29 (2022) 101699