Institute of Physics of Materials AS CR, v. v. i. > Projects > Vlastnosti nanoprášků připravených pulzním elektronovým svazkem při nízkém tlaku plynu

Vlastnosti nanoprášků připravených pulzním elektronovým svazkem při nízkém tlaku plynu

InvestigatorRNDr. Naděžda Pizúrová, Ph.D.
Number of Project21-31852J
AgencyGrantová agentura České republiky
Duration2021-01-01 - 2023-12-31

Anotace
The proposed project is focused on basic research with an impact on urgent biomedical applications. The development of new pharmaceutical products based on nanoparticles is a hot topic of current nanomaterial research. This effort is based on recent findings of serious toxicity of some agents currently used, and directed towards finding safer and more effective medical treatment using metal oxide nanoparticles, namely CeO2 for radiation oncology, Gd2O3 and MnO as contrast agents, ZnO and TiO2 as antitumor agents, Al2O3 and AgO as antibacterial agents, and Fe3O4/γFe2O3 for the hyperthermia treatment of cancer. The nanometric size and shape of nanoparticles are primarily responsible for their unique features; however, a surface quality (vacancies, defects) is equally important for the required properties. We suggest performing a fundamental experimental and theoretical study of the selected metal oxide nanopowders prepared using a unique physical method allowing for optimized nanopowder synthesis and modification of the surface for higher reactivity and increased biological activity.